Robetta is a protein structure prediction service that is continually evaluated through CAMEO
Features include an interactive submission interface that allows custom sequence alignments for homology modeling, constraints, local fragments, and more. It can model multi-chain complexes and provides the option for large scale sampling.
It uses the PDB100 template database, which is updated weekly, a co-evolution based model database (MDB), and also provides the option for custom templates.
Any feedback to help improve this service is greatly appreciated. You can submit feedback and bug reports using the form on our contact page.
Recent alerts and bug fixes:
August 5, 2019 - Job run times have been delayed due to filesystem and database issues. We are working on resolving these issues. Sorry for any inconvenience.
July 2, 2019 - We're experiencing issues with our filesystem and job distribution which have delayed jobs and may have affected single RosettaCM model jobs which were submitted from alignment cluster pages. If you recently submitted such jobs, you may have to resubmit by clicking the "Rosetta Model" link again. Sorry for any inconvenience.
June 5, 2019 - There was an issue with our filesystem which caused a delay in job run times. Sorry for any inconvenience.
May 31, 2019 - Thanks to Luki Goldschmidt for not only building, developing, and maintaining the computing infrastructure behind this service but for also creating the home page graphic. We've added the total number of models sampled per week along with the previously existing usage statistics displayed below.
May 1, 2019 - There was a bug in our contact page. Feel free to send us feedback.
April 11, 2019 - You can now view non-private jobs without having to log in. Fixed a bug on the submit page when trying to add constraints without a loaded template.
March 27, 2019 - Updated the PDB template upload reader to skip residues missing backbone atoms which cause Rosetta jobs to fail. When the input sequence is modified and in the rare case when the template(s) realignment fails, the templates will be removed.
March 22, 2019 - Fixed user provided partial thread input error where coordinates with no chain identifier would get skipped. Changed how multiple user provided partial threads were setup for RosettaCM. Previously they were structurally clustered and each cluster would be modeled separately. This was changed so multiple user provided partial threads are no longer clustered. All custom partial threads are now used in a single RosettaCM hybridize run.
Jobs queued: 77
New users last week: 119
New jobs last week: 288
New final models last week: 1185
Total models sampled last week: 22027763